|
KMID : 0380620220540030280
|
|
Korean Journal of Food Science and Technology
2022 Volume.54 No. 3 p.280 ~ p.287
|
|
|
Antioxidant and whitening effects of loquat (Eriobotrya japonica) fruit extracts
|
|
Yun Min-Kyu
Park Gi-Cheol
Cho Youn-Sup
Kim Dae-Ok
|
|
|
Abstract
|
|
|
|
The loquat (Eriobotrya japonica) is a fruit tree belonging to the Rosaceae family. Loquat fruit extracts from three cultivars (Tanaka, Mogi, and Jinwang) were prepared using absolute methanol and homogenization and ultrasound sonication procedures. We measured the total phenolic and flavonoid content of the fruit extracts and their antioxidant capacities. In addition, we evaluated tyrosinase activity and anti-melanogenic effects in B16F1 melanoma cells. The fruit extract from cv. Tanaka had the highest total phenolic content and showed the highest antioxidant capacity in the ABTS assay. The loquat fruit extract from cv. Jinwang had the highest total flavonoid content and showed the highest antioxidant capacity in the DPPH assay. Loquat fruit extracts from the Tanaka and Jinwang cultivars effectively inhibited mushroom tyrosinase activity. The loquat fruit extracts reduced intracellular oxidative stress in B16F1 melanoma cells. Treating B16F1 melanoma cells with loquat fruit extract from cv. Tanaka at a concentration of 125 μg/mL effectively inhibited melanin synthesis. However, treating the B16F1 melanoma cells with loquat fruit extracts from the Jinwang and Mogi cultivars did not. These results suggest that loquat fruit extracts from the Tanaka cultivar may serve as potential sources of antioxidants and act as a skin-whitening agent.
|
|
|
KEYWORD
|
|
|
antioxidant capacity, intracellular oxidative stress, loquat fruit, melanin, tyrosinase
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|